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PARP1 Blocking Peptide (N-term)

PARP1 Blocking Peptide (N-term)

Item no.	ABC-BP19834a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Majewski, P.M., et al. J. Biol. Chem. 285(45):34828-34838(2010) Kim, M., et al. Cancer Sci. 101(11):2436-2442(2010) Dong, Y., et al. Cancer Res. 70(20):8088-8096(2010) Krishnakumar, R., et al. Mol. Cell 39(5):736-749(2010) Lee, K.A., et al. Rheumatol. Int. (2010) In press :
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Poly [ADP-ribose] polymerase 1,PARP-1,ADP-ribosyltransferase diphtheria toxin-like 1,ARTD1,NAD(+) ADP-ribosyltransferase 1,ADPRT 1,Poly[ADP-ribose] synthase 1,PARP1,ADPRT,PPOL
Similar products	PARP1, PARP-1, PPOL, ADPRT, NAD(+) ADP-ribosyltransferase 1, Poly [ADP-ribose] polymerase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, ARTD1, ADP-ribosyltransferase diphtheria toxin-like 1
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 138-151 of HUMAN PARP1
Bio Background	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclearproteins by poly(ADP-ribosyl)ation. The modification is dependenton DNA and is involved in the regulation of various importantcellular processes such as differentiation, proliferation, andtumor transformation and also in the regulation of the molecularevents involved in the recovery of cell from DNA damage. Inaddition, this enzyme may be the site of mutation in Fanconianemia, and may participate in the pathophysiology of type Idiabetes.
Gene Name	PARP1 {ECO:0000303\|PubMed:21680843, ECO:0000312\|HGNC:HGNC:270}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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