NR3C1 Blocking Peptide (C-term)

Peptides; Blocking Peptides

The protein encoded by this gene is a receptor forglucocorticoids that can act as both a transcription factor and asa regulator of other transcription factors. This protein can alsobe found in heteromeric cytoplasmic complexes along with heat shockfactors and immunophilins. The protein is typically found in thecytoplasm until it binds a ligand, which induces transport into thenucleus. Mutations in this gene are a cause of glucocorticoidresistance, or cortisol, resistance. Alternate splicing, the use ofat least three different promoters, and alternate translationinitiation sites result in several transcript variants encoding thesame protein or different isoforms, but the full-length nature ofsome variants has not been determined.

Synthetic peptide