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p27Kip1 Blocking Peptide (N-term S12)

p27Kip1 Blocking Peptide (N-term S12)

Item no.	ABC-BP20014a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Kajihara, R., et al. Biochem. Biophys. Res. Commun. 401(3):350-355(2010) Kedde, M., et al. Nat. Cell Biol. 12(10):1014-1020(2010) Canbay, E., et al. Anticancer Res. 30(7):3093-3098(2010) Do Nascimento Borges, B., et al. In Vivo 24(4):579-582(2010) Qin, J., et al. Hepatogastroenterology 57 (99-100), 547-553 (2010) :
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cyclin-dependent kinase inhibitor 1B,Cyclin-dependent kinase inhibitor p27,p27Kip1,CDKN1B,KIP1
Similar products	p27Kip1, CDKN1B, KIP1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 5-19 of HUMAN CDKN1B
Bio Background	This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21.The encoded protein binds to and prevents the activation of cyclinE-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycleprogression at G1. The degradation of this protein, which istriggered by its CDK dependent phosphorylation and subsequentubiquitination by SCF complexes, is required for the cellulartransition from quiescence to the proliferative state. [provided byRefSeq].
Gene Name	CDKN1B {ECO:0000303\|PubMed:20824794}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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