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GPR77 Blocking Peptide (C-term)

GPR77 Blocking Peptide (C-term)

Item no.	ABC-BP20046b
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Neuroinflammation Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Bamberg, C.E., et al. J. Biol. Chem. 285(10):7633-7644(2010) Cui, W., et al. Mol. Immunol. 46(16):3207-3217(2009) Cui, W., et al. Mol. Immunol. 46(15):3086-3098(2009) Scola, A.M., et al. Mol. Immunol. 46(6):1149-1162(2009) Scola, A.M., et al. J. Biol. Chem. 282(6):3664-3671(2007)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	C5a anaphylatoxin chemotactic receptor 2,Complement component 5a receptor 2,G-protein coupled receptor 77,C5AR2,C5L2,GPR77
Similar products	GPR77, C5L2, G-protein coupled receptor 77, C5AR2, C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 312-325 of HUMAN C5AR2
Bio Background	The anaphylatoxins C3a (see MIM 120700), C4a (see MIM120810), and C5a are cationic fragments generated during thecomplement cascade that participate in host defense. In the case ofinappropriate complement activation, anaphylatoxins may be involvedin autoimmunity and sepsis. C5L2 is coexpressed with the C5areceptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophilsand may modulate C5AR activity (Gerard et al., 2005 [PubMed16204243]).
Gene Name	C5AR2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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