CASR Blocking Peptide (Center)

Peptides; Blocking Peptides

The protein encoded by this gene is a G protein-coupledreceptor that is expressed in the parathyroid hormone(PTH)-producing chief cells of the parathyroid gland, and the cellslining the kidney tubule. It senses small changes in circulatingcalcium concentration and couples this information to intracellularsignaling pathways that modify PTH secretion or renal cationhandling, thus this protein plays an essential role in maintainingmineral ion homeostasis. Mutations in this gene cause familialhypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided byRefSeq].

Synthetic peptide