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PSEN2 Blocking Peptide (N-term)

PSEN2 Blocking Peptide (N-term)

Item no.	ABC-BP20599a
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Protein Aggregation, Clearance & Misfolding Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Levy-Lahad E.,et al.Science 269:973-977(1995). Rogaev E.I.,et al.Nature 376:775-778(1995). Li J.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:12180-12184(1995). Levy-Lahad E.,et al.Genomics 34:198-204(1996). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Presenilin-2,PS-2,3423-,AD3LP,AD5,E5-1,STM-2,Presenilin-2 NTF subunit,Presenilin-2 CTF subunit,PSEN2,AD4,PS2,PSNL2,STM2
Similar products	PSEN2, AD3LP, AD5, E5-1, STM-2, AD4, PS2, PSNL2, STM2, PS-2, Presenilin-2, 3423-, Presenilin-2 NTF subunit, Presenilin-2 CTF subunit
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 52-65 of HUMAN PSEN2
Bio Background	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Gene Name	PSEN2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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