« Back
Home /
DNMT1 Blocking Peptide (N-term)

DNMT1 Blocking Peptide (N-term)

Item no.	ABC-BP20862a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Neural Epigenetics By Cell Type Hematology Lymphoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Yen R.-W.C.,et al.Nucleic Acids Res. 20:2287-2291(1992). Yoder J.A.,et al.J. Biol. Chem. 271:31092-31097(1996). Li L.C.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases. Grimwood J.,et al.Nature 428:529-535(2004). Hsu D.-W.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:9751-9756(1999).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DNA (cytosine-5)-methyltransferase 1,Dnmt1,CXXC-type zinc finger protein 9,DNA methyltransferase HsaI,DNA MTase HsaI,MHsaI,MCMT,DNMT1,AIM,CXXC9,DNMT
Similar products	Dnmt1, AIM, DNMT1, CXXC9, DNMT, DNA (cytosine-5)-methyltransferase 1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, MCMT, DNA MTase HsaI, MHsaI
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 363-376 of HUMAN DNMT1
Bio Background	Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.
Gene Name	DNMT1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-BP20862a-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 500 ug

available

Delivery expected until 11/6/2025

Express Delivery: Save 13 days

Compare

Add to wishlist

Get an offer