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EWSR1 Blocking Peptide (C-term)

EWSR1 Blocking Peptide (C-term)

Item no.	ABC-BP20984c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Delattre O.,et al.Nature 359:162-165(1992). Plougastel B.,et al.Genomics 18:609-615(1993). Zucman-Rossi J.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases. Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004). Ota T.,et al.Nat. Genet. 36:40-45(2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Similar products	EWSR1, EWS, RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein
Available
Primary Accession	Q01844
Bio Background	Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Bio References	Delattre O., et al.Nature 359:162-165(1992). Plougastel B., et al.Genomics 18:609-615(1993). Zucman-Rossi J., et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases. Collins J.E., et al.Genome Biol. 5:R84.1-R84.11(2004). Ota T., et al.Nat. Genet. 36:40-45(2004).
Gene ID	2130
Gene Name	EWSR1
Subtitle	Synthetic peptide
Other Accession	Q61545
Target/Specificity	The synthetic peptide sequence is selected from aa 639-654 of HUMAN EWSR1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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