« Back
Home /
SMURF2 Antibody (C-term) Blocking Peptide

SMURF2 Antibody (C-term) Blocking Peptide

Item no.	ABC-BP2105b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Cell Biology Cell Status Senescence Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Tajima, Y., et al., J. Biol. Chem. 278(12):10716-10721 (2003).Suzuki, C., et al., J. Biol. Chem. 277(42):39919-39925 (2002).Ebisawa, T., et al., J. Biol. Chem. 276(16):12477-12480 (2001).Zhu, H., et al., Nature 400(6745):687-693 (1999).Lambris, J., et al., J. Immunol. Methods 27(1):55-59 (1979).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	E3 ubiquitin-protein ligase SMURF2,hSMURF2,632-,SMAD ubiquitination regulatory factor 2,SMAD-specific E3 ubiquitin-protein ligase 2,SMURF2
Similar products	SMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, SMAD-specific E3 ubiquitin-protein ligase 2, hSMURF2, 632-
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP2105b was selected from the C-term region of human SMURF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	SMURF2 is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein interacts with SMAD1, SMAD2 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. It enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2. Coexpression of SMURF2 with SMAD1 results in considerable decrease in steady-state level of SMAD1 protein and a smaller decrease of SMAD2 level.
Gene Name	SMURF2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-BP2105b-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 500 ug

available

Delivery expected until 1/1/2026

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer