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ERCC2 Blocking Peptide (C-term)

ERCC2 Blocking Peptide (C-term)

Item no.	ABC-BP21175a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Metabolism Cholesterol & Lipid Metabolism By Cell Type Carcinoma Hematology Lymphoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Weber C.A.,et al.EMBO J. 9:1437-1447(1990). Lamerdin J.E.,et al.Genomics 34:399-409(1996). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Fletjer W.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:261-265(1992).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TFIIH basal transcription factor complex helicase XPD subunit,Basic transcription factor 2 80 kDa subunit,BTF2 p80,CXPD,DNA excision repair protein ERCC-2,DNA repair protein complementing XP-D cells,TFIIH basal transcription factor complex 80 kDa subunit,TFIIH 80 kDa subunit,TFIIH p80,Xeroderma pigmentosum group D-complementing protein,ERCC2,XPD,XPDC
Similar products	ERCC2, XPD, TFIIH basal transcription factor complex helicase XPD subunit, TFIIH p80, BTF2 p80, XPDC, CXPD, TFIIH 80 kDa subunit, Basic transcription factor 2 80 kDa subunit, DNA excision repair protein ERCC-2, DNA repair protein complementing XP-D cells, TFIIH basal transcription factor complex 80 kDa subunit, Xeroderma pigmentosum group D-complementing protein
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 687-702 of HUMAN ERCC2
Bio Background	ATP-dependent 5'-3' DNA helicase, component of the core- TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Gene Name	ERCC2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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