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CXCR4 Blocking Peptide (N-term)

CXCR4 Blocking Peptide (N-term)

Item no.	ABC-BP21194a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience By Cell Type Carcinoma Hematology Leukemia Lymphoma Peptides & Proteins Cardiovascular Research Atherosclerosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Herzog H.,et al.DNA Cell Biol. 12:465-471(1993). Jazin E.E.,et al.Regul. Pept. 47:247-258(1993). Federsppiel B.,et al.Genomics 16:707-712(1993). Loetscher M.,et al.J. Biol. Chem. 269:232-237(1994). Nomura H.,et al.Int. Immunol. 5:1239-1249(1993).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	C-X-C chemokine receptor type 4,CXC-R4,CXCR-4,FB22,Fusin,HM89,LCR1,Leukocyte-derived seven transmembrane domain receptor,LESTR,Lipopolysaccharide-associated protein 3,LAP-3,LPS-associated protein 3,NPYRL,Stromal cell-derived factor 1 receptor,SDF-1 receptor,CD184,CXCR4
Similar products	CD184, CXCR4, C-X-C chemokine receptor type 4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, NPYRL, Stromal cell-derived factor 1 receptor, CXC-R4, CXCR-4, SDF-1 receptor, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, LPS-associated protein 3
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 28-43 of HUMAN CXCR4
Bio Background	Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
Gene Name	CXCR4
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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