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FBXW7 Blocking Peptide (N-term)

FBXW7 Blocking Peptide (N-term)

Item no.	ABC-BP21312a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Winston J.T.,et al.Curr. Biol. 9:1180-1182(1999). Moberg K.H.,et al.Nature 413:311-316(2001). Strohmaier H.,et al.Nature 413:316-322(2001). Li J.,et al.J. Neurochem. 82:1540-1548(2002). Bechtel S.,et al.BMC Genomics 8:399-399(2007).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	F-box/WD repeat-containing protein 7,Archipelago homolog,hAgo,F-box and WD-40 domain-containing protein 7,F-box protein FBX30,SEL-10,hCdc4,FBXW7 ()
Similar products	F-box protein FBX30, SEL-10, Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box/WD repeat-containing protein 7, hAgo, hCdc4, FBXW7 (HGNC:16712)
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 133-147 of HUMAN FBXW7 ()
Bio Background	Substrate recognition component of an SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. Identified substrates include cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
Gene Name	FBXW7
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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