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ADAM15 Blocking Peptide (N-Term)

ADAM15 Blocking Peptide (N-Term)

Item no.	ABC-BP21324a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Kraetzschmar J.,et al.J. Biol. Chem. 271:4593-4596(1996). Herren B.,et al.FASEB J. 11:173-180(1997). Charrier L.,et al.Am. J. Physiol. 288:G346-G353(2005). Kleino I.,et al.BMC Mol. Biol. 8:90-90(2007). Zhong J.L.,et al.Mol. Cancer Res. 6:383-394(2008).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Disintegrin and metalloproteinase domain-containing protein 15, ADAM 15, 3424-, Metalloprotease RGD disintegrin protein, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, MDC-15, Metargidin, ADAM15, MDC15
Similar products	ADAM 15, ADAM15, Metalloproteinase-like, disintegrin-like, MDC15, and cysteine-rich protein 15, Disintegrin and metalloproteinase domain-containing protein 15, MDC-15, Metalloprotease RGD disintegrin protein, 3424-, Metargidin
Available
Primary Accession	Q13444
Bio Background	Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Bio References	Kraetzschmar J., et al.J. Biol. Chem. 271:4593-4596(1996). Herren B., et al.FASEB J. 11:173-180(1997). Charrier L., et al.Am. J. Physiol. 288:G346-G353(2005). Kleino I., et al.BMC Mol. Biol. 8:90-90(2007). Zhong J.L., et al.Mol. Cancer Res. 6:383-394(2008).
Gene ID	8751
Gene Name	ADAM15
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence is selected from aa 37-52 of HUMAN ADAM15

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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