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MLF1 Blocking Peptide (C-term)

MLF1 Blocking Peptide (C-term)

Item no.	ABC-BP21370b
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Adenocarcinoma Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Yoneda-Kato N.,et al.Oncogene 12:265-275(1996). Feng X.,et al.Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Muzny D.M.,et al.Nature 440:1194-1198(2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Myeloid leukemia factor 1,Myelodysplasia-myeloid leukemia factor 1,MLF1
Similar products	MLF1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 216-230 of HUMAN MLF1
Bio Background	Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Gene Name	MLF1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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