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SRY Blocking Peptide (Center)

SRY Blocking Peptide (Center)

Item no.	ABC-BP21539c
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Sinclair A.H.,et al.Nature 346:240-244(1990). Su H.,et al.Am. J. Hum. Genet. 52:24-38(1993). Behlke M.A.,et al.Genomics 17:736-739(1993). Whitfield L.S.,et al.Genomics 27:306-311(1995). Ferrari S.,et al.EMBO J. 11:4497-4506(1992).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Sex-determining region Y protein,Testis-determining factor,SRY,TDF
Similar products	SRY, TDF, Sex-determining region Y protein, Testis-determining factor
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 81-92 of HUMAN SRY
Bio Background	Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
Gene Name	SRY {ECO:0000303\|PubMed:1695712, ECO:0000312\|HGNC:HGNC:11311}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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