Comparison

ITGA2B(Integrin alpha-IIb heavy chain) Blocking Peptide (C-term)

Item no. ABC-BP21648b
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Lyophilized
Specific against other
Citations Poncz M.,et al.J. Biol. Chem. 262:8476-8482(1987).
Frachet P.,et al.Mol. Biol. Rep. 14:27-33(1990).
Heidenreich R.,et al.Biochemistry 29:1232-1244(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Integrin alpha-IIb,GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb,CD41,Integrin alpha-IIb heavy chain,Integrin alpha-IIb light chain,form 1,Integrin alpha-IIb light chain,form 2,ITGA2B,GP2B,ITGAB
Similar products ITGA2B, CD41, GP2B, GPIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, ITGAB, form 2, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb heavy chain
Available
Manufacturer - Category
Peptides; Blocking Peptides
Manufacturer - Targets
The synthetic peptide sequence is selected from aa 803-817 of HUMAN ITGA2B
Bio Background
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Gene Name
ITGA2B
Subtitle
Synthetic peptide
Formulation
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
available

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