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KANK2 Blocking Peptide (Center)

KANK2 Blocking Peptide (Center)

Item no.	ABC-BP21691c
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Zhang Y.,et al.EMBO J. 26:2645-2657(2007). Zhu Y.,et al.Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases. Nagase T.,et al.DNA Res. 7:143-150(2000). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KN motif and ankyrin repeat domain-containing protein 2,Ankyrin repeat domain-containing protein 25,Matrix-remodeling-associated protein 3,SRC-1-interacting protein,SIP,SRC-interacting protein,SRC1-interacting protein,KANK2,ANKRD25,KIAA1518,MXRA3,SIP
Similar products	KANK2, SIP, ANKRD25, KIAA1518, MXRA3, KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25, Matrix-remodeling-associated protein 3, SRC-1-interacting protein, SRC1-interacting protein, SRC-interacting protein
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 363-376 of HUMAN KANK2
Bio Background	Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500). May be involved in promotion of cell proliferation (By similarity).
Gene Name	KANK2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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