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CACNA1A Blocking Peptide (Center)

CACNA1A Blocking Peptide (Center)

Item no.	ABC-BP21701c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Hans M.,et al.Biophys. J. 76:1384-1400(1999). Ophoff R.A.,et al.Cell 87:543-552(1996). Zhuchenko O.,et al.Nat. Genet. 15:62-69(1997). Toru S.,et al.J. Biol. Chem. 275:10893-10898(2000). Grimwood J.,et al.Nature 428:529-535(2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Brain calcium channel I, BI, Calcium channel, L type, alpha-1 polypeptide isoform 4, Voltage-gated calcium channel subunit alpha Cav21, CACNA1A, CACH4, CACN3, CACNL1A4
Similar products	CACNL1A4, L type, BI, Brain calcium channel I, Calcium channel, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, CACNA1A, alpha-1 polypeptide isoform 4, Voltage-gated calcium channel subunit alpha Cav21, CACH4, CACN3
Available
Primary Accession	O00555
Bio Background	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin- IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).
Bio References	Hans M., et al.Biophys. J. 76:1384-1400(1999). Ophoff R.A., et al.Cell 87:543-552(1996). Zhuchenko O., et al.Nat. Genet. 15:62-69(1997). Toru S., et al.J. Biol. Chem. 275:10893-10898(2000). Grimwood J., et al.Nature 428:529-535(2004).
Gene ID	773
Gene Name	CACNA1A (HGNC:1388)
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence is selected from aa 918-932 of HUMAN CACNA1A

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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