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GRIN2B Blocking Peptide (C-Term)

GRIN2B Blocking Peptide (C-Term)

Item no.	ABC-BP21859b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Adams S.L.,et al.Biochim. Biophys. Acta 1260:105-108(1995). Hess S.D.,et al.J. Pharmacol. Exp. Ther. 278:808-816(1996). Mandich P.,et al.Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases. Mandich P.,et al.Genomics 22:216-218(1994). Schito A.M.,et al.Neurosci. Lett. 239:49-53(1997).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Glutamate receptor ionotropic, NMDA 2B, GluN2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B, N-methyl-D-aspartate receptor subunit 3, NR3, hNR3, GRIN2B, NMDAR2B
Similar products	NR2B, NMDAR2B, GRIN2B, Glutamate receptor ionotropic, NR3, hNR3, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, GluN2B, NMDA 2B
Available
Primary Accession	Q13224
Bio Background	NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Bio References	Adams S.L., et al.Biochim. Biophys. Acta 1260:105-108(1995). Hess S.D., et al.J. Pharmacol. Exp. Ther. 278:808-816(1996). Mandich P., et al.Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases. Mandich P., et al.Genomics 22:216-218(1994). Schito A.M., et al.Neurosci. Lett. 239:49-53(1997).
Gene ID	2904
Gene Name	GRIN2B
Subtitle	Synthetic peptide
Other Accession	Q01097; Q00960
Target/Specificity	The synthetic peptide sequence is selected from aa 1320-1332 of HUMAN GRIN2B

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/2/2025

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