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RSPO3 Blocking Peptide (C-Term)

RSPO3 Blocking Peptide (C-Term)

Item no.	ABC-BP21989b
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Chen J.-Z.,et al.Mol. Biol. Rep. 29:287-292(2002). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mungall A.J.,et al.Nature 425:805-811(2003). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Kim K.-A.,et al.Cell Cycle 5:23-26(2006).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	R-spondin-3,Protein with TSP type-1 repeat,hPWTSR,Roof plate-specific spondin-3,hRspo3,Thrombospondin type-1 domain-containing protein 2,RSPO3,PWTSR,THSD2
Similar products	PWTSR, THSD2, RSPO3, R-spondin-3, hPWTSR, hRspo3, Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 217-230 of HUMAN RSPO3
Bio Background	Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
Gene Name	RSPO3
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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