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Phospho-MEK6(S202) Antibody Blocking peptide

Phospho-MEK6(S202) Antibody Blocking peptide

Item no.	ABC-BP3162a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	MAP2K6, MKK6, Dual specificity mitogen-activated protein kinase kinase 6, MAPK/ERK kinase 6, SAPKK3, MEK6, PRKMK6, SKK3, MAP kinase kinase 6, MAPKK 6, MEK 6, Stress-activated protein kinase kinase 3, SAPK kinase 3, SAPKK-3
Available
Primary Accession	P52564
Bio Background	This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Bio References	Gensch, E., et al., J. Biol. Chem. 279(37):39085-39093 (2004).Woo, J.H., et al., Oncogene 23(10):1845-1853 (2004).Dirsch, V.M., et al., Oncogene 23(8):1586-1593 (2004).Ho, D.T., et al., J. Biol. Chem. 278(35):32662-32672 (2003).Sundarrajan, M., et al., Arthritis Rheum. 48(9):2450-2460 (2003).
Gene ID	5608
Gene Name	MAP2K6
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP3162a was selected from the 252-265 region of human Phospho-MEK6-S202. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/2/2025

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