Phospho-CCNB3(T280) Blocking Peptide

Peptides; Blocking Peptides

The protein encoded by this gene belongs to the highlyconserved cyclin family, whose members are characterized by adramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases. Different cyclinsexhibit distinct expression and degradation patterns whichcontribute to the temporal coordination of each mitotic event.Studies of similar genes in chick and Drosophila suggest that thiscyclin may associate with CDC2 and CDK2 kinases, and be requiredfor proper spindle reorganization and restoration of the interphasenucleus. Two transcript variants encoding different isoforms havebeen found for this gene.

Synthetic peptide