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FE65 (APBB1) Antibody (C-term) Blocking peptide

FE65 (APBB1) Antibody (C-term) Blocking peptide

Item no.	ABC-BP6100a
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Kinoshita, A., et al., J. Biol. Chem. 278(42):41182-41188 (2003).Walsh, D.M., et al., Biochemistry 42(22):6664-6673 (2003).Zhao, Q., et al., Biochemistry 42(12):3627-3634 (2003).Hu, Q., et al., Hum. Mol. Genet. 11(4):465-475 (2002).Bruni, P., et al., J. Biol. Chem. 277(38):35481-35488 (2002).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Amyloid beta A4 precursor protein-binding family B member 1,Protein Fe65,APBB1,FE65,RIR
Similar products	FE65, APBB1, RIR, Protein Fe65, Amyloid beta A4 precursor protein-binding family B member 1
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6100a was selected from the C-term region of human APBB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	APBB1 is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression.
Gene Name	APBB1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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