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MLLT1 Antibody (C-term) Blocking Peptide

MLLT1 Antibody (C-term) Blocking Peptide

Item no.	ABC-BP6188a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Myelofibrosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Nie, Z., et al., Mol. Cell. Biol. 23(8):2942-2952 (2003).Lavau, C., et al., Proc. Natl. Acad. Sci. U.S.A. 97(20):10984-10989 (2000).Thirman, M.J., et al., Proc. Natl. Acad. Sci. U.S.A. 91(25):12110-12114 (1994).Rubnitz, J.E., et al., Blood 84(6):1747-1752 (1994).Yamamoto, K., et al., Oncogene 8(10):2617-2625 (1993).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Protein ENL,YEATS domain-containing protein 1,MLLT1,ENL,LTG19,YEATS1
Similar products	MLLT1, ENL, LTG19, YEATS1, Protein ENL, YEATS domain-containing protein 1
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6188a was selected from the C-term region of human MLLT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11; 19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.
Gene Name	MLLT1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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