Comparison

SIRT1 Antibody (C-term) Blocking Peptide

Item no. ABC-BP6240a
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Lyophilized
Specific against other
Citations Takata, T., et al., Biochem. Biophys. Res. Commun. 301(1):250-257 (2003).Bitterman, K.J., et al., J. Biol. Chem. 277(47):45099-45107 (2002).Langley, E., et al., EMBO J. 21(10):2383-2396 (2002).Frye, R.A., Biochem. Biophys. Res. Commun. 273(2):793-798 (2000).Frye, R.A., Biochem. Biophys. Res. Commun. 260(1):273-279 (1999).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NAD-dependent protein deacetylase sirtuin-1,hSIRT1,351-,Regulatory protein SIR2 homolog 1,SIR2-like protein 1,hSIR2,SirtT1 75 kDa fragment,75SirT1,SIRT1,SIR2L1
Similar products SIRT1, SIR2L1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIR2, 75SirT1, SirtT1 75 kDa fragment, 351-
Available
Manufacturer - Category
Peptides; Blocking Peptides
Manufacturer - Targets
The synthetic peptide sequence used to generate the antibody AP6240a was selected from the C-term region of human SIRT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background
SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Gene Name
SIRT1 {ECO:0000303|PubMed:12535671, ECO:0000312|HGNC:HGNC:14929}
Subtitle
Synthetic peptide
Formulation
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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