Comparison

APP Antibody (N-term) Blocking Peptide

Item no. ABC-BP6306a
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Lyophilized
Specific against other
Citations Borroni, B., et al., Arch. Neurol. 60(12):1740-1744 (2003).Lleo, A., et al., J. Biol. Chem. 278(48):47370-47375 (2003).Zhou, Y., et al., Science 302(5648):1215-1217 (2003).Murakami, K., et al., J. Biol. Chem. 278(46):46179-46187 (2003).Kim, J.Y., et al., Biochem. Biophys. Res. Commun. 310(3):904-909 (2003).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Amyloid beta A4 protein,ABPP,APPI,APP,Alzheimer disease amyloid protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II,N-APP,Soluble APP-alpha,S-APP-alpha,Soluble APP-beta,S-APP-beta,C99,Beta-amyloid protein 42,Beta-APP42,Beta-amyloid protein 40,Beta-APP40,C83,P3(42),P3(40),C80,Gamma-secretase C-terminal fragment 59,Amyloid intracellular domain 59,AICD-59,AID(59),Gamma-CTF(59),Gamma-secretase C-terminal fragment 57,Amyloid intracellular domain 57,AICD-57,AID(57),Gamma-CTF(57),Gamma-secretase C-terminal fragment 50,Amyloid intracellular domain 50,AICD-50,AID(50),Gamma-CTF(50),C31,APP,A4,AD1
Similar products APP, A4, AD1, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, N-APP, Soluble APP-alpha, Soluble APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, CVAP, Beta-APP40, Beta-amyloid protein 40, PN-II, C31, C80, C83, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Amyloid intracellular domain 50, Amyloid intracellular domain 57, Amyloid intracellular domain 59, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), S-APP-alpha, S-APP-beta, P3(42), P3(40), Gamma-secretase C-terminal fragment 59, Gamma-secretase C-terminal fragment 57, Gamma-secretase C-terminal fragment 50
Available
Manufacturer - Category
Peptides; Blocking Peptides
Manufacturer - Targets
The synthetic peptide sequence used to generate the antibody AP6306a was selected from the N-term region of human APP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Gene Name
APP
Subtitle
Synthetic peptide
Formulation
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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