Mouse Kif5C-1 Antibody (C-term) Blocking Peptide

Peptides; Blocking Peptides

Kinesins are microtubule-based motor proteins involved in the transport of organelles in eukaryotic cells. They typically consist of 2 identical, approximately 110- to 120-kD heavy chains and 2 identical, approximately 60- to 70-kD light chains. The heavy chain contains 3 domains: a globular N-terminal motor domain, which converts the chemical energy of ATP into a motile force along microtubules in 1 fixed direction; a central alpha-helical rod domain, which enables the 2 heavy chains to dimerize; and a globular C-terminal domain, which interacts with light chains and possibly an organelle receptor.

Synthetic peptide