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RBL2/p130 Antibody (Center) Blocking Peptide

RBL2/p130 Antibody (Center) Blocking Peptide

Item no.	ABC-BP6543c
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Peptides & Proteins Peptides By Organ Brain Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Priya,K., Cancer Biol. Ther. 8 (8), 714-717 (2009)Fields,A.L., J. Cell. Physiol. 217 (1), 77-85 (2008)Masciullo,V., Clin. Cancer Res. 14 (15), 4775-4779 (2008)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Retinoblastoma-like protein 2,130 kDa retinoblastoma-associated protein,p130,Retinoblastoma-related protein 2,RBR-2,pRb2,RBL2,RB2
Similar products	RBL2, RB2, Retinoblastoma-like protein 2, 130 kDa retinoblastoma-associated protein, Retinoblastoma-related protein 2, pRb2, p130, RBR-2
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6543c was selected from the Center region of human RBL2/p130. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	RBL2 is a key regulator of entry into cell division. The protein is directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. It recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. It controls histone H4 'Lys-20' trimethylation. It probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.
Gene Name	RBL2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP6543c-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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