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DNA PK (PRKDC) Antibody (C-term) Blocking peptide

DNA PK (PRKDC) Antibody (C-term) Blocking peptide

Item no.	ABC-BP7053b
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Goudelock, D.M., et al., J. Biol. Chem. 278(32):29940-29947 (2003).Ding, Q., et al., Mol. Cell. Biol. 23(16):5836-5848 (2003).Lucero, H., et al., J. Biol. Chem. 278(24):22136-22143 (2003).Calsou, P., et al., J. Mol. Biol. 326(1):93-103 (2003).Karpova, A.Y., et al., Proc. Natl. Acad. Sci. U.S.A. 99(5):2818-2823 (2002).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DNA-dependent protein kinase catalytic subunit,DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460,PRKDC,HYRC,HYRC1
Similar products	PRKDC, DNPK1, DNA-PKcs, HYRC, HYRC1, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, p460
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7053b was selected from the C-term region of human PRKDC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]
Gene Name	PRKDC
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7053b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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