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LRRK2 (PARK8) Mutant G2019S Antibody Blocking Peptide

LRRK2 (PARK8) Mutant G2019S Antibody Blocking Peptide

Item no.	ABC-BP7100a
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Ozelius,L.J. et al. N. Engl. J. Med. 354 (4), 424-425 (2006)Lesage,S. et al. N. Engl. J. Med. 354 (4), 422-423 (2006)Smith,W.W. et al. Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18676-18681 (2005)Bialecka,M. et al. Neurosci. Lett. 390 (1), 1-3 (2005)Hernandez,D. et al. Neurosci. Lett. 389 (3), 137-139 (2005)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Leucine-rich repeat serine/threonine-protein kinase 2,Dardarin,LRRK2,PARK8
Similar products	LRRK2, PARK8, Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7100a was selected from the PARK8 region of human LRRK2 (PARK8) Mutant G2019S. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	LRRK2 is a member of the leucine-rich repeat kinase family. The protein possesses an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in thisgene have been associated with Parkinson disease-8.
Gene Name	LRRK2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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