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Pyruvate Kinase (PKM2) Antibody (C-term N491) Blocking peptide

Pyruvate Kinase (PKM2) Antibody (C-term N491) Blocking peptide

Item no.	ABC-BP7173a
Manufacturer	Abcepta
Amount	500 ug
Category	Metabolism Glucose Homeostasis Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Lehner, B., et al., Genome Res. 14(7):1315-1323 (2004).Gevaert, K., et al., Nat. Biotechnol. 21(5):566-569 (2003).Valentini, G., et al., J. Biol. Chem. 277(26):23807-23814 (2002).Lowrie, D.J. Jr., et al., J. Struct. Biol. 132(2):83-94 (2000).Williams, J.M., et al., Mol. Microbiol. 27(1):171-186 (1998).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Pyruvate kinase PKM,Cytosolic thyroid hormone-binding protein,CTHBP,Opa-interacting protein 3,OIP-3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Thyroid hormone-binding protein 1,THBP1,Tumor M2-PK,p58,PKM,OIP3,PK2,PK3,PKM2
Similar products	PKM2, PKM, OIP3, PK2, PK3, Cytosolic thyroid hormone-binding protein, Opa-interacting protein 3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, Tumor M2-PK, p58, CTHBP, THBP1, Pyruvate kinase PKM, OIP-3
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7173a was selected from the C-term region of human PKM2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Gene Name	PKM
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7173a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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