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MAPK14 Antibody (T180/Y182) Blocking Peptide

MAPK14 Antibody (T180/Y182) Blocking Peptide

Item no.	ABC-BP7226f
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	MAPK14, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, CSBP, CSBP1, CSBP2, CSPB1, SAPK2A, MAX-interacting protein 2, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, MAP kinase MXI2, MAP kinase p38 alpha, Stress-activated protein kinase 2a, MXI2, SAPK2a
Available
Primary Accession	Q16539
Bio Background	MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
Bio References	Cheung, P.C., et al., EMBO J. 22(21):5793-5805 (2003).Dean, J.L., et al., J. Biol. Chem. 278(41):39470-39476 (2003).Sun, A., et al., Exp. Neurol. 183(2):394-405 (2003).Yustein, J.T., et al., Oncogene 22(40):6129-6141 (2003).Frevel, M.A., et al., Mol. Cell. Biol. 23(2):425-436 (2003).
Gene ID	1432
Gene Name	MAPK14
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP7226f was selected from the T180/Y182 region of human MAPK14. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/2/2025

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