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REA (PHB2) Antibody (N-term) Blocking peptide

REA (PHB2) Antibody (N-term) Blocking peptide

Item no.	ABC-BP7270a
Manufacturer	Abcepta
Amount	500 ug
Category	Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Obesity Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Takata,H., Curr. Biol. 17 (15), 1356-1361 (2007)Kasashima,K., J. Biol. Chem. 281 (47), 36401-36410 (2006)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Prohibitin-2,B-cell receptor-associated protein BAP37,D-prohibitin,Repressor of estrogen receptor activity,PHB2 {ECO:0000312\|EMBL:AAH147661,ECO:0000312\|HGNC:HGNC:30306}
Similar products	Prohibitin-2, D-prohibitin, B-cell receptor-associated protein BAP37, Repressor of estrogen receptor activity, PHB2 {ECO:0000312\|EMBL:AAH147661, ECO:0000312\|HGNC:HGNC:30306}
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7270a was selected from the N-term region of human PHB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
Gene Name	PHB2 {ECO:0000312\|EMBL:AAH14766.1, ECO:0000312\|HGNC:HGNC:30306}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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