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IDH1 Antibody (Center) Blocking Peptide

IDH1 Antibody (Center) Blocking Peptide

Item no.	ABC-BP7454c
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Myelofibrosis Astrocytoma Peptides By Organ Brain Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Geisbrecht B.V., Gould S.J.J. Biol. Chem. 274:30527-30533(1999)Xu X., Zhao J., Xu Z.J. Biol. Chem. 279:33946-33957(2004) Bleeker F.E., Lamba S.Hum. Mutat. 30:7-11(2009)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Isocitrate dehydrogenase [NADP] cytoplasmic,IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,IDH1,PICD
Similar products	IDH1, IDH, IDP, PICD, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate dehydrogenase [NADP] cytoplasmic, Oxalosuccinate decarboxylase, NADP(+)-specific ICDH
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7454c was selected from the Center region of human IDH1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Gene Name	IDH1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7454c-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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