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CDK5 Antibody (C-term) Blocking Peptide

CDK5 Antibody (C-term) Blocking Peptide

Item no.	ABC-BP7521b
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling By Cell Type Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Hamdane, M., et al., J. Biol. Chem. 278(36):34026-34034 (2003).Noble, W., et al., Neuron 38(4):555-565 (2003).Augustinack, J.C., et al., J. Neuropathol. Exp. Neurol. 61(6):557-564 (2002).Filgueira de Azevedo, W. Jr., et al., Biochem. Biophys. Res. Commun. 297(5):1154-1158 (2002).Patzke, H., et al., J. Biol. Chem. 277(10):8054-8060 (2002).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cyclin-dependent-like kinase 5,Cell division protein kinase 5,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit,CDK5,CDKN5
Similar products	CDK5, Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit, CDKN5
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7521b was selected from the C-term region of human CDK5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	Cyclin dependent kinase 5 (CdK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. CDK5 is most abundant in neuronal and muscle cells contain the highest amount of this protein. Cdk5 is not activated by cyclins, but by the p35 protein, which is expressed solely in the brain. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
Gene Name	CDK5
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7521b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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