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CDK7 Antibody (C-term) Blocking Peptide

CDK7 Antibody (C-term) Blocking Peptide

Item no.	ABC-BP7523b
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Kino, T., et al., Biochem. Biophys. Res. Commun. 298(1):17-23 (2002).Schneider, E., et al., Oncogene 21(33):5031-5037 (2002).Bochar, D.A., et al., J. Biol. Chem. 274(19):13162-13166 (1999).Akoulitchev, S., et al., Genes Dev. 12(22):3541-3550 (1998).Yee, A., et al., Cancer Res. 55(24):6058-6062 (1995).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cyclin-dependent kinase 7,39 kDa protein kinase,p39 Mo15,CDK-activating kinase 1,Cell division protein kinase 7,Serine/threonine-protein kinase 1,TFIIH basal transcription factor complex kinase subunit,CDK7,CAK,CAK1,CDKN7,MO15,STK1
Similar products	CDK7, CAK, CAK1, CDKN7, MO15, STK1, Cyclin-dependent kinase 7, 39 kDa protein kinase, CDK-activating kinase 1, Cell division protein kinase 7, Serine/threonine-protein kinase 1, TFIIH basal transcription factor complex kinase subunit, p39 Mo15
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7523b was selected from the C-term region of human CDK7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Gene Name	CDK7
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7523b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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