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ALK Antibody (N-term) Blocking Peptide

ALK Antibody (N-term) Blocking Peptide

Item no.	ABC-BP7600a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Peptides & Proteins Adenocarcinoma Astrocytoma Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Morris, S.W., et al., Oncogene 14(18):2175-2188 (1997).Iwahara, T., et al., Oncogene 14(4):439-449 (1997).Morris, S.W., et al., Science 263(5151):1281-1284 (1994).Morris, S.W., et al., Oncogene 15, 2883-2883 (1997).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,CD246,ALK
Similar products	ALK, ALK tyrosine kinase receptor, CD246, Anaplastic lymphoma kinase
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7600a was selected from the N-term region of human ALK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2; 5)(p23; q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Gene Name	ALK {ECO:0000303\|PubMed:9174053, ECO:0000312\|HGNC:HGNC:427}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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