Comparison

EphB6 Antibody (C-term H990) Blocking Peptide

Item no. ABC-BP7627b
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products Ephrin type-B receptor 6, Tyrosine-protein kinase-defective receptor EPH-6, EPHB6, HEP
Available
Primary Accession
O15197
Bio Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Bio References
Freywald, A., et al., J. Biol. Chem. 278(12):10150-10156 (2003). Luo, H., et al., J. Clin. Invest. 110(8):1141-1150 (2002). Wilkinson, D.G., Nat Rev Neurosci 2(3):155-164 (2001). Luo, H., et al., J. Immunol. 167(3):1362-1370 (2001). Tang, X.X., et al., Proc. Natl. Acad. Sci. U.S.A. 97(20):10936-10941 (2000).
Gene ID
2051
Gene Name
EPHB6
Subtitle
Synthetic peptide
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP7627b was selected from the C-terminal region with histidine at position 990 of human EphB6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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