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ERBB2 Antibody(C-term Y1248) Blocking peptide

ERBB2 Antibody(C-term Y1248) Blocking peptide

Item no.	ABC-BP7629d
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Ehsani, A., et al., Genomics 15(2):426-429 (1993).Yamamoto, T., et al., Nature 319(6050):230-234 (1986).Coussens, L., et al., Science 230(4730):1132-1139 (1985).Semba, K., et al., Proc. Natl. Acad. Sci. U.S.A. 82(19):6497-6501 (1985).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Receptor tyrosine-protein kinase erbB-2,Metastatic lymph node gene 19 protein,MLN 19,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Tyrosine kinase-type cell surface receptor HER2,p185erbB2,CD340,ERBB2,HER2,MLN19,NEU,NGL
Similar products	ERBB2, Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, Tyrosine kinase-type cell surface receptor HER2, MLN 19, HER2, NEU, NGL, MLN19, Metastatic lymph node gene 19 protein, CD340
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7629d was selected from the Y1248 region of human ERBB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Gene Name	ERBB2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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