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IGF1 Receptor (IGF1R) Antibody (N-term) Blocking peptide

IGF1 Receptor (IGF1R) Antibody (N-term) Blocking peptide

Item no.	ABC-BP7649a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism By Cell Type Blastoma Carcinoma Peptides & Proteins Endocrine Regulation of Lipid Metabolism Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Song, R.X., et al., Proc. Natl. Acad. Sci. U.S.A. 101(7):2076-2081 (2004).Zhao, H., et al., Oncogene 23(3):786-794 (2004).Lu, Y., et al., Biochem. Biophys. Res. Commun. 313(3):709-715 (2004).Hakam, A., et al., Dig. Dis. Sci. 48(10):1972-1978 (2003).Li, Y., et al., Arterioscler. Thromb. Vasc. Biol. 23(12):2178-2184 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Insulin-like growth factor 1 receptor,Insulin-like growth factor I receptor,IGF-I receptor,CD221,Insulin-like growth factor 1 receptor alpha chain,Insulin-like growth factor 1 receptor beta chain,IGF1R
Similar products	IGF1R, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain, CD221, IGF-I receptor
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7649a was selected from the N-term region of human IGF1R. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Gene Name	IGF1R
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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