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RET Antibody (C-term T1078) Blocking Peptide

RET Antibody (C-term T1078) Blocking Peptide

Item no.	ABC-BP7669b
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Peptides & Proteins Adenocarcinoma Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Da Silva, A.M., et al., J. Clin. Endocrinol. Metab. 88(11):5438-5443 (2003).McWhinney, S.R., et al., J. Clin. Endocrinol. Metab. 88(10):4911-4916 (2003).D'Alessio, A., et al., Endocrinology 144(10):4298-4305 (2003).Soares, P., et al., Oncogene 22(29):4578-4580 (2003).Punales, M.K., et al., J. Clin. Endocrinol. Metab. 88(6):2644-2649 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Proto-oncogene tyrosine-protein kinase receptor Ret,Cadherin family member 12,Proto-oncogene c-Ret,Soluble RET kinase fragment,Extracellular cell-membrane anchored RET cadherin 120 kDa fragment,RET,CDHF12,CDHR16,PTC,RET51
Similar products	RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7669b was selected from the C-term region of human RET. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Gene Name	RET {ECO:0000303\|PubMed:2660074, ECO:0000312\|HGNC:HGNC:9967}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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