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TEK (TIE2) Antibody (C-term) Blocking peptide

TEK (TIE2) Antibody (C-term) Blocking peptide

Item no.	ABC-BP7684a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Adenocarcinoma Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Cascone, I., et al., Blood 102(7):2482-2490 (2003).DeBusk, L.M., et al., Arthritis Rheum. 48(9):2461-2471 (2003).Poncet, S., et al., Neuropathol Appl Neurobiol 29(4):361-369 (2003).Lee, H.J., et al., Biochem. Biophys. Res. Commun. 304(2):399-404 (2003).Sussman, L.K., et al., Cancer Biol. Ther. 2(3):255-256 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Angiopoietin-1 receptor,Endothelial tyrosine kinase,Tunica interna endothelial cell kinase,Tyrosine kinase with Ig and EGF homology domains-2,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,hTIE2,p140 TEK,CD202b,TEK,TIE2,VMCM,VMCM1
Similar products	TEK, TIE2, VMCM, VMCM1, Angiopoietin-1 receptor, Endothelial tyrosine kinase, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains-2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK, CD202b, hTIE2
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7684a was selected from the C-term region of human TEK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Gene Name	TEK
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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