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NTRK1 Antibody (Y791) Blocking Peptide

NTRK1 Antibody (Y791) Blocking Peptide

Item no.	ABC-BP7686d
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides By Organ Thyroid Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Tokusashi, Y., et al., Int. J. Cancer 114(1):39-45 (2005).Schulte, J.H., et al., Oncogene 24(1):165-177 (2005).Frattini, M., et al., Oncogene 23(44):7436-7440 (2004).Tacconelli, A., et al., Cancer Cell 6(4):347-360 (2004).Florenes, V.A., et al., Am. J. Clin. Pathol. 122(3):412-420 (2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	High affinity nerve growth factor receptor,Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA,NTRK1,MTC,TRK,TRKA
Similar products	NTRK1, MTC, TRK, TRKA, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, p140-TrkA, Trk-A
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7686d was selected from the Y791 region of human NTRK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	NTRK1 (also known as TRKA)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Gene Name	NTRK1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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