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SMAD4 Antibody (T277) Blocking Peptide

SMAD4 Antibody (T277) Blocking Peptide

Item no.	ABC-BP7753a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Carcinoma Peptides & Proteins Adenocarcinoma Peptides By Organ Colorectal Cancer
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Sekiya, T., et al., Biochem. Biophys. Res. Commun. 320(3):680-684 (2004).Horvath, L.G., et al., Prostate 59(3):234-242 (2004).Li, L., et al., Mol. Cell. Biol. 24(2):856-864 (2004).Wan, M., et al., J. Biol. Chem. 279(15):14484-14487 (2004).Maru, D., et al., Oncogene 23(3):859-864 (2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mothers against decapentaplegic homolog 4,MAD homolog 4,Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,SMAD 4,Smad4,hSMAD4,SMAD4,DPC4,MADH4
Similar products	SMAD4, Smad4, DPC4, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, SMAD 4, hSMAD4
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7753a was selected from the T277 region of human SMAD4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Gene Name	SMAD4
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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