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DAXX Antibody (S495) Blocking Peptide

DAXX Antibody (S495) Blocking Peptide

Item no.	ABC-BP7773a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	Daxx, DAXX, BING2, DAP6, Death domain-associated protein 6, ETS1-associated protein 1, Fas death domain-associated protein, EAP1, hDaxx
Available
Primary Accession	Q9UER7
Bio Background	DAXX is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, this protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, this protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.
Bio References	Cantrell, S.R., et al., J. Virol. 79(12):7792-7802 (2005).Greger, J.G., et al., J. Virol. 79(8):4610-4618 (2005).Chang, C.C., et al., J. Biol. Chem. 280(11):10164-10173 (2005).Beausoleil, S.A., et al., Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135 (2004).Gostissa, M., et al., J. Biol. Chem. 279(46):48013-48023 (2004).
Gene ID	1616
Gene Name	DAXX
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP7773a was selected from the S495 region of humanXX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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