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ACVRL1 Antibody (C-term) Blocking Peptide

ACVRL1 Antibody (C-term) Blocking Peptide

Item no.	ABC-BP7807b
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Berg, J.N., et al., Am. J. Hum. Genet. 61(1):60-67 (1997).Johnson, D.W., et al., Nat. Genet. 13(2):189-195 (1996).ten Dijke, P., et al., Oncogene 8(10):2879-2887 (1993).Attisano, L., et al., Cell 75(4):671-680 (1993).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Serine/threonine-protein kinase receptor R3,SKR3,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I,ACVRL1,ACVRLK1,ALK1
Similar products	ACVRL1, TGF-B superfamily receptor type I, ACVRLK1, ALK1, Serine/threonine-protein kinase receptor R3, Activin receptor-like kinase 1, ALK-1, SKR3, TSR-I
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7807b was selected from the C-term region of human ACVRL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Gene Name	ACVRL1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7807b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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