« Back
Home /
ALOX5 Antibody (C-term) Blocking Peptide

ALOX5 Antibody (C-term) Blocking Peptide

Item no.	ABC-BP7856b
Manufacturer	Abcepta
Amount	500 ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Enzymes Peptides Leukotriene Metabolism
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Mahshid,Y., BMC Immunol. 10, 2 (2009)Koeberle,A., J. Med. Chem. 51 (24), 8068-8076 (2008)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Arachidonate 5-lipoxygenase,5-LO,5-lipoxygenase,ALOX5,LOG5
Similar products	5-lipoxygenase, ALOX5, 5-LO, LOG5, Arachidonate 5-lipoxygenase
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7856b was selected from the C-term region of human ALOX5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	ALOX5 is a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8, 11, 14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7, 9-trans-11, 14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of ALOX5 gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers.
Gene Name	ALOX5
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-BP7856b-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 500 ug

available

Delivery expected until 11/6/2025

Express Delivery: Save 14 days

Compare

Add to wishlist

Get an offer