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BCL2L10 Antibody (Center) Blocking Peptide

BCL2L10 Antibody (Center) Blocking Peptide

Item no.	ABC-BP7877c
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Peptides & Proteins Cell Biology Cell Status Apoptosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Kolluri,S.K., Cancer Cell 14 (4), 285-298 (2008)Krajewska,M., Clin. Cancer Res. 14 (10), 3011-3021 (2008)Zhai,D., J. Biol. Chem. 283 (15), 9580-9586 (2008)Ke,N., J. Biol. Chem. 276 (16), 12481-12484 (2001)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Bcl-2-like protein 10,Bcl2-L-10,Anti-apoptotic protein NrH,Apoptosis regulator Bcl-B,BCL2L10,BCLB
Similar products	BCL2L10, Anti-apoptotic protein NrH, Apoptosis regulator Bcl-B, Bcl-2-like protein 10, Bcl2-L-10, BCLB
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7877c was selected from the Center region of human BCL2L10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of BCL2L10 gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation.
Gene Name	BCL2L10 {ECO:0000303\|PubMed:17532299}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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