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CYP2D6 Antibody (Center) Blocking Peptide

CYP2D6 Antibody (Center) Blocking Peptide

Item no.	ABC-BP7882c
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	de Leon,J., CNS Spectr 14 (1), 19-34 (2009)Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cytochrome P450 2D6,CYPIID6,Cytochrome P450-DB1,Debrisoquine 4-hydroxylase,CYP2D6,CYP2DL1
Similar products	CYP2D6, CYP2DL1, Cytochrome P450 2D6, CYPIID6, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7882c was selected from the Center region of human CYP2D6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant.
Gene Name	CYP2D6 {ECO:0000303\|PubMed:21289075, ECO:0000312\|HGNC:HGNC:2625}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP7882c-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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