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ITPKA Antibody (C-term) Blocking Peptide

ITPKA Antibody (C-term) Blocking Peptide

Item no.	ABC-BP8166b
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Gonzalez, B., et al., Mol. Cell 15(5):689-701 (2004).Mishra, J., et al., Biophys. J. 83(3):1298-1316 (2002).Schell, M.J., et al., J. Biol. Chem. 276(40):37537-37546 (2001).Communi, D., et al., EMBO J. 16(8):1943-1952 (1997).Woodring, P.J., et al., J. Biol. Chem. 272(48):30447-30454 (1997).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Inositol-trisphosphate 3-kinase A,Inositol 1,5-trisphosphate 3-kinase A,IP3 3-kinase A,IP3K A,InsP 3-kinase A,ITPKA
Similar products	Inositol 1, ITPKA, Inositol-trisphosphate 3-kinase A, 5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP8166b was selected from the C-term region of human ITPKA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
Gene Name	ITPKA
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP8166b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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